How does it work?
The MACS procedure involves several key steps:
Semen Sample Preparation
We collect the semen sample as normal. The sample is obtained through ejaculation and collected in a sterile container provided by us.
Density Gradient Centrifugation
The semen sample undergoes density gradient centrifugation, a commonly used method to separate sperm cells from the seminal fluid and other debris. This step helps remove dead or immotile sperm, as well as potential contaminants.
Antibody-Coated Magnetic Beads
Special magnetic beads coated with antibodies that specifically target proteins on the surface of severely damaged sperm cells are introduced to the sample. These beads bind to the undesirable sperm, forming bead-sperm complexes.
Magnetic Separation
The sample is passed through a column placed in a magnetic field. The magnet attracts the bead-sperm complexes, while the healthy sperm cells flow through unaffected.
What are the Benefits of MACS
MACS offers several advantages over traditional sperm selection methods. Many studies have been done in the use of MACS for men with high degrees of DNA fragmentation. The advantage that this technique offers is the reduction on risks of miscarriage which is the hardest consequence for couples with high DNA damage.